Project Coordinator: Assist. Prof. Hasan Uluşan

Project Type: TUBITAK 1001

Project Budget: 2.400.000 TL

Project Duration: 30 Months

Project Start Date: 01 November 2025

Funded Personnel: 1 Master Student (full-time), 2 MSc Students (part-time)

Current methods used in the treatment of peripheral nerve injuries (PNI) often provide limited effectiveness and fail to achieve permanent recovery. The PeriFiks Project offers an innovative approach to PNI treatment by developing a new generation of MEMS-based micro biosensors and stimulation systems with micro-scale, high-precision, and wireless capabilities. This approach provides advantages such as higher spatial selectivity, low impedance, long-term stability, and biocompatibility. Unlike existing technologies, this project proposes the use of flexible and biocompatible materials, optimized for intrafascicular placement. PeriFiks demonstrates innovative potential in PNI rehabilitation with features such as high signal-to-noise ratio, low impedance, spatial selectivity, and wireless power and data transmission. Within the scope of PeriFiks, MEMS-based microelectrode arrays will be developed and integrated with a closed-loop stimulation and recording system. The closed-loop stimulation and recording system will be developed with a structure incorporating an analog front-end and a wireless communication module. This system will be tested in ex-vivo animal models to evaluate both detailed analysis of afferent and efferent nerve activities and placement stability.